We consider holographic description of heavy ions collisions. The dependence of total multiplicity on the energy forcing us to deal with anisotropic holographic models. We derive the holographic renorm group flow (HRGF) equations in the presentce of anisotropy and a non-zero chemical potential. We show that in particular cases HRGFs reproduce the QCD RGFs. We consider the behaviour of the Wilson loops in the constructed backgrounds and find the form of the anisotropic QCD phase diagrams.